Nickel (metallic) (Cancer)

Nickel (metallic) is listed under California Proposition 65 for the Cancer endpoint. Its established safe harbor level is 0.8 µg/day as a NSRL, determined for exposure primarily via the inhalation route. CAS registry number: 7440-02-0.

Safe Harbor Level

What this level means

A NSRL is a daily exposure level for Nickel (metallic) that — at or below 0.8 µg/day per day — does not require a Proposition 65 warning because it poses no significant risk for the Cancer endpoint. This is the No Significant Risk Level (NSRL) — the daily intake for the cancer endpoint.

• Level: 0.8 µg/day per day (NSRL).
• Endpoint: Cancer.
• Route: exposure is assessed primarily through the inhalation route.
• CAS: 7440-02-0.

Businesses that expose consumers to more than the safe harbor level for Nickel (metallic) must provide a clear and reasonable Prop 65 warning. Compliance is assessed against the applicable OEHHA safe harbor level above; where no safe harbor level is established, an exposure assessment may be required.

Compliance notes

1. Compare the daily exposure to the NSRL of 0.8 µg/day.
2. If exposure exceeds the level, a Prop 65 warning is generally required.
3. Confirm the current OEHHA listing and any updates to the level before relying on it — safe harbor levels are amended periodically.

Frequently Asked Questions

What is the Prop 65 safe harbor level for Nickel (metallic)?

0.8 µg/day per day (NSRL).

What is the CAS number for Nickel (metallic)?

7440-02-0.

What endpoint is Nickel (metallic) listed for?

Cancer.

What is the primary route of exposure for Nickel (metallic)?

The inhalation route.

What is the difference between an NSRL and a MADL?

An NSRL (No Significant Risk Level) applies to cancer endpoints; a MADL (Maximum Allowable Dose Level) applies to reproductive and developmental endpoints.